Thursday 13th May
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08.30 - 09.00 |
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Join the meeting and networking (DMDG Virtual Coffee Area)
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09.00 - 09.10 |
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Introductions (Auditorium)
Sarah Armstrong – Charles River and DMDG Apprentice Committee
Member
followed by
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09.10 - 09.20
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Jamie Henshall – UCB and DMDG Chair Elect 2021-22
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09.20 - 09.45 |
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Breakout groups - introductions and ice-breaker activities
(Breakout Rooms)
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09.45 - 10.00 |
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Bring-your-own-coffee and networking (DMDG Virtual Coffee Area)
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10.00 - 10.50 |
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Poster Blitz Session (Auditorium)
Chair: Amelia Taibon-Kuer, Sygnature Discovery
- Liam Curry, Certara
Development and verification of a Physiologically Based Pharmacokinetic (PBPK) model to simulate lansoprazole exposure and Drug-Drug interactions in Caucasian and Japanese populations
- Louisa O’Grady, Astex
The validation of P-gp efflux inhibitors using the Caco-2 assay
- Alex Williams, Cyprotex
Validation of a Membrane Vesicle Methodology to Assess MRP2, MRP3 and MRP4 Inhibition: Characterisation of Probe Substrate Transport Properties and Implications for Experimental Design
- Chloe Lorenzo, Sygnature Discovery
Development of an Equilibrium Gel Filtration Assay to Quantify the Plasma Protein Binding of Highly Bound Drugs
- Claire Purdy, Charles River
Analysis of in vitro DMPK Samples Using High Throughput ADDA-Sciex Trap and Elute LC-MS/MSTechnology–Is This The Lab of The Future?
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10.50 - 11.20 |
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Bring-your-own-coffee and poster viewing (Online Poster Room)
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11.20 - 12.20 |
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First speaker session (Auditorium)
Chair: Claire Purdy, Charles River
- Amelia Taibon-Kuer, Sygnature Discovery
Development and Validation of an In Vitro Hepatocyte Metabolic Stability Assay for Low Turnover Compounds
- Chloe Whitehouse, University of Nottingham
Blood-Brain Barrier “on-a-Chip” model for Testing Drug Permeability into the Brain
- Jessie Stow, Astex
The 3Rs in DMPK: are we doing all that we can?
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12.20 - 12.35 |
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Return to breakout rooms to discuss morning sessions (Breakout Rooms)
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12.35 - 13.30 |
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Bring-your-own-lunch, poster viewing and networking (DMDG
Virtual Coffee Area & Online Poster Room)
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13.30 - 14.30 |
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Industry Insights Session (Auditorium)
Chair: Sarah Bailey, Cyprotex Discovery Ltd
- Simon Taylor, Pharmaron
- Karelle Menochet, UCB
- Tim Schulz-Utermoehl, Pandeia Therapeutics
- Dawn Yates, Charles River
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14.30 - 15.00 |
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Discussions in breakout rooms - set topics to discuss (Breakout Rooms)
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15.00 - 15.30 |
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Bring-your-own-coffee and poster viewing (Online Poster Room)
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15.30 - 16.10 |
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Second speaker session (Auditorium)
Chair: Chloe Whitehouse, University of Nottingham
- Sarah Bailey, Cyprotex
Use of Stable Label Glutathione as an Additional Diagnostic Measure for the Screening of Reactive Metabolite Formation in Microsome and S9 Fractions using the Glutathione Trapping Method
- Blandine Grisard, LGC Group
Pre-analytical challenges observed during the development of an LC-MS/MS method for coproporphyrin I and copropophyrin III in human plasma
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16.10 - 16.25 |
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Return to breakout rooms to discuss afternoon sessions (Breakout Rooms)
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16.25 - 16.45 |
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Final poster viewing (Online Poster Room)
- Vote for your favourite presentation from the two Speaker
Sessions and for your favourite poster - a link will be provided
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16.45 - 17.00 |
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Prizes and closing remarks (Auditorium)
Sarah Armstrong – Charles River and DMDG Apprentice Committee
Member
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17.00 - 17.30 |
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Virtual Coffee Area will remain open for 30 minutes
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